GO Grant to Establish International Database for Genomic Imbalances in Autism and other Developmental Disorders
An NICHD Grand Opportunities (GO) grant has been awarded to Emory University investigators David H. Ledbetter, PhD (PI) and Christa Lese Martin, PhD (co-PI), both in the Department of Human Genetics, to establish an international database of clinical and genetic data from patients with autism and other developmental disorders. This two year, $3.4M grant includes collaborators at Columbia University, George Washington University, the University of California-Santa Cruz, the Mayo Clinic, and GeneDx. The grant will support infrastructure and software tool development to allow efficient collection of clinical and genetic data in standardized formats on 50-100,000 patients/year undergoing genetic diagnostic testing as part of their routine clinical care. It will also support development of advanced data integration and visualization tools to provide researchers and clinicians with user-friendly access to these large datasets for data mining and clinical interpretation of genetic test results.